产品货号：
Z38874
中文名称：
UPF1抗体
英文名称：
Anti-UPF1 Antibody (Clone#11E7)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UPF1 Antibody (Clone#11E7) |
| 指标别名 | UPF1 RNA helicase and ATPase;HUPF1;NORF1;RENT1;pNORF1;smg-2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | UPF1 |
| 克隆号 | 11E7 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human RENT1/hUPF1 (578-614aa NMDSMPELQKLQQLKDETGELSSADEKRYRALKRT AE),identical to the related mouse and rat sequences. |
| 实际分子量 | 130KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Regulator of nonsense transcripts 1 is a protein that in humans is encoded by the UPF1 gene.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).When translation ends upstream from the last exon-exon junction,this triggers NMD to degrade mRNAs containing premature stop codons.And this protein is located only in the cytoplasm.When translation ends,it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.Use of multiple polyadenylation sites has been noted for this gene.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | Q92900 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | UPF1 regulator of nonsense transcripts homolog (yeast) |
| 蛋白名全称 | Regulator of nonsense transcripts 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：UPF1抗体，UPF1单抗，Anti-UPF1 Antibody (Clone#11E7)